A new study conducted by the Center for Addiction and Mental Health (CAMH), Bordeaux University Hospital, France, and the World Health Organization (WHO) has found that individuals with alcohol use disorder who undergo rehabilitation or maintain abstinence are significantly less likely to developing alcohol. -associated cancers.
The work, titled “Alcohol rehabilitation and cancer risk: a nationwide hospital-based cohort study in France,” was published in The Lancet Public Health. It is the largest of its kind to provide evidence linking reduced or discontinued alcohol consumption to a reduced risk of all alcohol-attributable cancers, including liver and throat cancer.
The nationwide retrospective cohort study analyzed data from more than 24 million French people, all adults living in mainland France and discharged from hospitals between 2018 and 2021. The researchers found that approximately 6.3% of men and 1.6% of women were alcohol dependent. was strongly associated with alcohol-related cancers, including hepatocellular carcinoma, as well as oral, pharyngeal, laryngeal, esophageal, and colorectal cancers, in both sexes.
However, they also found that rehabilitation treatment or a history of abstinence was associated with significantly lower risks compared to alcohol dependence without rehabilitation or abstinence. This underlines the effectiveness of treatment strategies in combating cancer risks associated with alcohol addiction.
“The research team was surprised by the magnitude of the effect of treatment interventions in this study,” said Dr. Jürgen Rehm, senior scientist at CAMH’s Institute for Mental Health Policy Research and senior author of the study. “We know that treatment for alcohol dependence is effective, but the fact that alcohol dependence is a relapsing chronic disease often makes us forget that even in relapse, periods of abstinence significantly reduce the risk of cancer and other chronic diseases.”
“From a public health perspective, our study highlights a disturbing neglect of alcohol addiction compared to other health issues in both research and policy priorities,” added lead author of the paper Dr. Michaël Schwarzinger, Department of Prevention, Bordeaux University Hospital. “As a result, alcohol dependence remains a silent, terrible epidemic in countries like France, especially given that the average annual level of alcohol consumption among adults in that country is more than twice the global average.”
“We know that the most effective strategy to reduce the overall burden of harm caused by alcohol, including cancer, lies in population-level policies – measures such as increasing alcohol taxes, reducing the availability of alcohol and banning or restricting marketing,” said Dr Carina Ferreira-Borges, Regional Advisor for Alcohol, Illicit Drugs and Prison Health at the WHO Regional Office for Europe.
“However, this study underlines that the response of healthcare systems is also crucial to reducing the risk of alcohol-attributable cancers. By increasing the accessibility of alcohol rehabilitation and abstinence interventions in healthcare, countries could do more to protect their populations from preventable cancers. We therefore call for increased investment in rehabilitation and treatment services for alcohol use disorders in France and other countries of the WHO European Region.”
Dr. Leslie Buckley, Head of Addictions at CAMH, emphasized the importance of these findings, stating: “In Canada, hospital admissions for alcohol-attributable conditions exceed those for myocardial infarction, and many people face barriers to evidence-based treatment if result of stigma and challenges in accessing in-person care Innovations such as virtual treatment can overcome these challenges by offering flexible and cost-effective solutions. At CAMH, we are researching fully virtual day programs that show promise and replicate traditional rehabilitation intensity without the need for physical infrastructure, reducing wait times and making treatment more accessible.
“Given the looming increase in alcohol availability in Ontario, it is essential to consider how we can make treatment more accessible. Greater alcohol availability will likely lead to increased consumption, and accessible virtual treatment programs could address this by providing critical care to those in need.”
More information:
Alcohol rehabilitation and cancer risk: a nationwide hospital-based cohort study in France, The Lancet Public Health (2024). www.thelancet.com/journals/lan … (24)00124-5/fulltext
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